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Ambroxol hydrochloride

CAS No. 23828-92-4

Ambroxol hydrochloride( NA 872 | Abrohexal | Ambril | Ambro-Puren Ambrobeta | Duramucal | Ebromin | Mucosolvan )

Catalog No. M13688 CAS No. 23828-92-4

Ambroxol HCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ambroxol hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Ambroxol HCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block.
  • Description
    Ambroxol HCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NA 872 | Abrohexal | Ambril | Ambro-Puren Ambrobeta | Duramucal | Ebromin | Mucosolvan
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    23828-92-4
  • Formula Weight
    414.56
  • Molecular Formula
    C13H18Br2N2O·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 3 mg/mL (7.23 mM)
  • SMILES
    OC1CCC(N(C2=CC(Br)=CC(Br)=C2N)C)CC1.[H]Cl
  • Chemical Name
    4-((2-amino-3,5-dibromophenyl)(methyl)amino)cyclohexan-1-ol hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Weiser T, et al. Mol Pharmacol, 2002, 62(3), 433-438.
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